Born and raised in West Virginia, Margo graduated from Michigan State College in 1970 with a degree in Medical Technology. Working in this field for 13 years, she then changed 'needles' and opened her first fabric store in 1983. She currently owns a brick and mortar/web business called ReproductionFabrics.com.

In 1996, Margo returned to college, pursuing extended studies in history at Montana State University and textile/quilt history with professors from the University of Nebraska-Lincoln and the University of Rhode Island. In 1997, she acquired the amazing early 19th Century Dargate Book, full of more than 2100 vintage fabric sample, many from which she draws her inspiration for her fabric designs.

Margo calls Bozeman, Montana her home when she is not lecturing and teaching on textile history around the country.